Usage of Ginkgo in Treatment of Deafness

Abstract

Background: Sudden deafness is an unexplained, abrupt loss of hearing that occurs either all at once or over a few days. Within the preparation of determination and treatment, it can be isolated into low-frequency, high-frequency slipped sort, flat PTA sort, and deafness sort. Objectives: This work explores the efficacy of Ginkgo biloba extract combined with hormones in treatment of sudden deafness and its action and changing of PTA hearing enhancement in feeling the fullness of the ear and vertigo and tinnitus. Materials and Methods: In this work, 56 patients with sudden deafness who were treated in The General Hospital of Al-Musayyib from August 2019 to August 2022 were selected. These patients were randomly divided into a hormone group (treatment with prednisone acetate, n =27) and a combination group (treatment with Ginkgo- combined with prednisone acetate, n =29). After the two groups of patients were treated in different ways, their efficacy, symptom improvement, and changes in (pure tone audiometry) PTA were compared. Results: The total effective rates (TERs) of the hormone group and the combination group were 76.32% and 95.73%, respectively (P <0:05). PTA improvements of the patients in the combination group were higher than those in the hormone group after 5 d, 7 d, and 14 d of treatment (P <0:05). The high PTA improvement values of patients in the combination group at 5 d, 7 d, and 14 d after treatment were greatly higher than those in the hormone group (P <0:05). There was no visible difference in the incidence of adverse reactions between the two groups of patients after treatment (P >0:05). Conclusion: the combined application of Ginkgo biloba extract and hormones could effectively improve the abnormal hearing indexes of patients with sudden deafness and effectively relieve the imbalance and hearing.

Keywords: Sudden deafness, Ginkgo biloba, PTA.